NAD+ Frequently Asked Questions

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in all living cells. Essential for energy metabolism, DNA repair via sirtuins and PARPs, and cellular signalling. ORYN NAD+ is formulated at >99% purity with 500 mg in a precision pen system.

NAD+ functions as an electron carrier in mitochondrial energy production, substrate for sirtuin enzymes (SIRT1-7) regulating gene expression and cellular stress responses, and substrate for PARP enzymes in DNA repair. NAD+ levels decline approximately 50% between ages 40 and 60.

Studied in cellular aging, mitochondrial function, DNA repair, neurodegenerative diseases, metabolic health, circadian rhythm regulation, cardiovascular function, and immune cell metabolism. One of the most actively researched molecules in longevity science.

Via a pre-mixed pen containing 500 mg in 3 mL. Subcutaneous injection delivers directly to the bloodstream, bypassing the digestive system which can degrade NAD+. No reconstitution required.

Manufactured to >99% purity under GMP-certified conditions with ISO 7 cleanroom standards. Each batch verified by independent HPLC and mass spectrometry. Certificates of Analysis provided for all batches.

Store refrigerated at 2-8°C, protected from light. Do not freeze. NAD+ is sensitive to heat and light degradation — proper storage is essential. Shelf life 24 months.

Commonly studied alongside Glutathione and GHK-Cu. Some researchers also study NAD+ with GH-releasing peptides. Protocol design should be based on published literature. Research information only.

Each ORYN NAD+ pen provides a full 30-day dosing protocol. The 500 mg / 3 mL formulation delivers precise daily doses over the complete monthly cycle.

Oral NAD+ precursors (NMN, NR) must be converted through multi-step enzymatic pathways, with significant losses during digestion. Injectable NAD+ delivers the active coenzyme directly, bypassing conversion steps and GI degradation, raising plasma levels far more rapidly.

Legal to purchase in the UK for research purposes. A naturally occurring coenzyme, not a controlled substance. ORYN supplies pharmaceutical-grade NAD+ for laboratory and research applications.